2020

Schneible, J.D., K. Shi, A.T. Young, S. Ramesh, N. He, C.E. Dowdey, R.L. Lilova, W. Gao, E. Santiso, M. Daniele, and S. Menegatti*, Modified Graphene Oxide (GO) Particles in Peptide Hydrogels: A Hybrid System Enabling Scheduled Delivery of Synergistic Combinations of Chemotherapeutics. Journal of Materials Chemistry B, 2020. 6(8): p. 3852-3868. 

Reese, H.R., T. Bordelon, F. Odeh, A. Broussard, C. Kormos, A. Murphy, C. Shanahan, and S. Menegatti*, Purification of animal immunoglobulin G (IgG) using peptoid affinity ligands. Biotechnology progress, 2020 

Reese, H., T. Bordelon, C. Shanahan, M. Crapanzano, J. Sly, and S. Menegatti*, Novel peptoid-based adsorbents for purifying IgM and IgG from polyclonal and recombinant sources. Journal of Chromatography B, 2020. 1137: p. 121909. 

Reese, H.R., C.C. Shanahan, C. Proulx, and S. Menegatti*, Peptide science: A “rule model” for new generations of peptidomimetics. Acta Biomaterialia, 2020. 102: p. 35-74. 

Reese, H.R., C.C. Shanahan, J. Lembo, L. Tsonev, A. Hirsh, and S. Menegatti*, Chromatographic assay to probe the binding energy and mechanisms of homologous proteins to surface-bound ligands. Journal of Chromatography B, 2020. 1136: p. 121927. 

Lavoie, R.A., A. di Fazio, T.I. Williams, R. Carbonell, and S. Menegatti*, Targeted capture of Chinese hamster ovary host cell proteins: Peptide ligand binding by proteomic analysis. Biotechnology and Bioengineering, 2020. 117(2): p. 438-452. 

Gilbertie, J.M., T.P. Schaer, A.G. Schubert, M.E. Jacob, S. Menegatti, R. Ashton Lavoie, and L.V. Schnabel, Platelet-rich plasma lysate displays anti-biofilm properties and restores antimicrobial activity against synovial fluid biofilms in vitro. Journal of Orthopaedic Research, 2020. 38(6): p. 1365-1374. 

Cutright, C., Z. Brotherton, L. Alexander, J. Harris, K. Shi, S. Khan, J. Genzer, and S. Menegatti*, Packing density, homogeneity, and regularity: Quantitative correlations between topology and thermoresponsive morphology of PNIPAM-co-PAA microgel coatings. Applied Surface Science, 2020. 508: p. 145129. 

Reese, H.R., X. Xiao, C.C. Shanahan, G.A. Van Den Driessche, D. Fourches, R.G. Carbonell, C.K. Hall, and S. Menegatti*, Novel peptide ligands for antibody purification provide superior clearance of host cell protein impurities, Journal of Chromatography A, 2020. 1625: p. 461237. 

Barozzi, A., K. Day, R. Prodromou, A. Lavoie, and S. Menegatti*, Affibody-binding ligands, International Journal of Molecular Sciences, 2020. 21(11): p. 3769. 

Day, K., J. D. Schneible, A. T. Young, V. A. Pozdin, G. Van Der Driessche, L. A. Gaffney, R. Prodromou, D. O. Freytes, D. Fourches, M. Daniele, and S. Menegatti*, Photoinduced reconfiguration to control the protein-binding affinity of azobenzene-cyclized peptides, Journal of Materials Chemistry B, 2020 

Raghuvanshi, K., C. Zhu, M. Ramezani, S. Menegatti, E. Santiso, D. Mason, J. Rodgers, M. Janka, and M. Abolhasani, Highly Efficient 1-Octene Hydroformylation at Low Syngas Pressure: From Single Droplet Screening to Continuous Flow Synthesis, ACS catalysis, 2020. 10(14): p. 7535-7542. 

Schneible, John, A. Young, M. Daniele, and S. Menegatti*, Chitosan Hydrogels for Synergistic Delivery of Chemotherapeutics to Triple Negative Breast Cancer Cells and Spheroids, Pharmacetical Research, 2020. 13(37): p. 142. 

Bowen, J.D., J. Schneible, C. Labar, S. Menegatti*, and B.M. Rao*, Screening of yeast display libraries of enzymatically-cyclized peptides to discover macrocyclic peptide ligands, Bioarxiv, 2020 

Bowen, J.D., K. Bacon, H.R. Reese, B.M. Rao, and S. Menegatti*, Use of target-displaying magnetized yeast in screening mRNA display peptide libraries to identify ligands, Bioarxiv, 202 

Bacon, K., A. Blain, J. Bowen, M. Burroughs, N. McArthur, S. Menegatti, B.M. Rao*, Quantitative yeast-yeast two hybrid for discovery and binding affinity estimation of protein- protein interactions, Bioarxiv, 2020. 

Kaitlyn Bacon, Ashton Lavoie, Bali M. Rao, Michael Daniele, Stefano Menegatti. “Past, Present, and Future of Affinity-based Cell Separation Technologies” Acta Biomaterialia, Vol 108

2019

Hannah Reese, Michael Daniele, Stefano Menegatti. “Mechanically controlled thermodynamics of biorecognition events.” American Chemical Society, Vol. 257

John Schneible, Ankush Singhal, Radina Lilova, Carol Hall, Andrea Grafmueller, Stefano Menegatti. “Integrated approach for tailoring chitosan hydrogels towards kinetically-tuned release of synergistic combinations of chemotherapeutics.” American Chemical Society, Vol 257

Ashton Lavoie, Alice di Fazio, Kevin Blackburn, David Muddiman, Michael Goshe, Ruben Carbonell, Stefano Menegatti. “Mixed-mode peptide ligands for improved clearance of CHO host cell proteins.” American Chemical Society, Vol. 257

Hannah Reese, Xingqing Xiao, Carol Hall, Stefano Menegatti. “Toward a true Protein A mimetic: new peptide affinity ligand for IgG purification afford high HCP LRV.” American Chemical Society, Vol. 257

John Schneible, Kaihang Shi, Erik Santiso, Keith Gubbins, Stefano Menegatti. “Tuning the surface chemisrtry of graphene oxide nanoparticles for controlling drug release: modeling and experiments.” American Chemical Society, Vol. 257

John D Schneible, Ankush Singhal, Radina L Lilova, Carol K Hall, Andrea Grafmüller, Stefano Menegatti. “Tailoring the Chemical Modification of Chitosan Hydrogels to Fine-Tune the Release of a Synergistic Combination of Chemotherapeutics.” Biomacromolecules (2019): 3126-3141

Kaitlyn Bacon, Matthew Burroughs, Abigail Blain, Stefano Menegatti, Balaji M Rao. “Screening yeast display libraries against magnetized yeast cell targets enables efficient isolation of membrane protein binders.” Journal of Chromatography A (2019): 284-299

Bordelon, Tee, Benjamin Bobay, Andrew Murphy, Hannah Reese, Calvin Shanahan, Fuad Odeh, Amanda Broussard, Chad Kormos, and Stefano Menegatti. “Translating IgG-binding peptides into peptoid ligands with improved affinity and stability.” Journal of Chromatography A, accepted for publication May 24th, 2019.

Saberi-Bosari, Sahand, Mohammad Omary, Ashton Lavoie, Raphael Prodromou, Kevin Day, Stefano Menegatti, and Adriana San-Miguel. “Affordable Microfluidic Bead-Sorting Platform for Automated Selection of Porous Particles Functionalized with Bioactive Compounds.” Scientific reports9, no. 1 (2019): 7210.

Lavoie, R. Ashton, Alice di Fazio, R. Kevin Blackburn, Michael B. Goshe, Ruben G. Carbonell, and Stefano Menegatti. “Targeted Capture of Chinese Hamster Ovary Host Cell Proteins: Peptide Ligand Discovery.” International journal of molecular sciences 20, no. 7 (2019): 1729.

Islam, Tuhidul, Amith Naik, Yasuhiro Hashimoto, Stefano Menegatti, and Ruben Carbonell. “Optimization of Sequence, Display, and Mode of Operation of IgG-Binding Peptide Ligands to Develop Robust, High-Capacity Affinity Adsorbents That Afford High IgG Product Quality.” International Journal of Molecular Sciences 20, no. 1 (2019): 161.

Pusuluri, Anusha, Vinu Krishnan, Valerie Lensch, Apoorva Sarode, Elaine Bunyan, Douglas R. Vogus, Stefano Menegatti, H. Tom Soh, and Samir Mitragotri. “Treating Tumors at Low Drug Doses Using an Aptamer–Peptide Synergistic Drug Conjugate.” Angewandte Chemie International Edition 58, no. 5 (2019): 1437-1441.

Naik, Amith D., Tuhidul Islam, Takaaki Terasaka, Yuki Ohara, Yasuhiro Hashimoto, Stefano Menegatti, and Ruben Carbonell. “Silica resins and peptide ligands to develop disposable affinity adsorbents for antibody purification.” Biochemical Engineering Journal 145 (2019): 53-61.

2018

Islam, Tuhidul, Amith Naik, Yasuhiro Hashimoto, Stefano Menegatti, and Ruben Carbonell. “Optimization of Sequence, Display, and Mode of Operation of IgG-Binding Peptide Ligands to Develop Robust, High-Capacity Affinity Adsorbents That Afford High IgG Product Quality.” International Journal of Molecular Sciences 20, no. 1 (2019): 161, doi:10.3390/ijms20010161

Pusuluri, Anusha, Vinu Krishnan, Valerie Lensch, Apoorva Sarode, Elaine Bunyan, Douglas Vogus, Stefano Menegatti, H. Tom Soh, and Samir Mitragotri. “Treating tumors at low drug doses using an aptamer‐peptide synergistic drug conjugate.” Angewandte Chemie International Edition (2018), doi:10.1002/anie.201812650

Wilkins, Michael D., Brendan L. Turner, Kristina R. Rivera, Stefano Menegatti, and Michael Daniele. “Quantum dot enabled lateral flow immunoassay for detection of cardiac biomarker NT-proBNP.” Sensing and Bio-Sensing Research(2018),doi:10.1016/j.sbsr.2018.10.002

Naik, Amith D., Tuhidul Islam, Takaaki Terasaka, Yuki Ohara, Yasuhiro Hashimoto, Stefano Menegatti, and Ruben Carbonell. “Silica resins and peptide ligands to develop disposable affinity adsorbents for antibody purification.” Biochemical Engineering Journal (2018), doi:10.1016/j.bej.2018.07.011

William S Kish, Mathew K. Roach, Hiroyuki Sachi, Amith D Naik, Stefano Menegatti, Ruben G Carbonell, “Purification of human erythropoietin by affinity chromatography using cyclic peptide ligands” J.Chromb. Release 2018,  doi: 10.1016/j.jchromb.2018.03.039.

2017

Mahmud, Marzana, Hannah Reese, A. Joshipura, C. Seok, Feysel Yamaner, Michael Daniele, Stefano Menegatti, and Omer Oralkan. “Gravimetric biosensor based on a capacitive micromachined ultrasonic transducer functionalized with peptide ligands.” In 2017 IEEE SENSORS, pp. 1-3. IEEE, 2017.

Douglas R. Vogus, Michael A. Evans, Anusha Pusuluri, Alexandra Barajas, Mengwen Zhang, Vinu Krishnan, Maksymilian Nowak, Stefano Menegatti, Matthew E. Helgeson, Todd M. Squires, Samir Mitragotri, “A hyaluronic acid conjugate engineered to synergistically and sequentially deliver gemcitabine and doxorubicin to treat triple negative breast cancer,” J. Control. Release 2017,In Press, Corrected Proof. doi: /10.1016/j.jconrel.2017.08.016

William S Kish, Hiroyuki Sachi, Amith D Naik, Matthew K Roach, Benjamin G Bobay, Robert K Blackburn, Stefano Menegatti, Ruben G Carbonell, “Design, selection, and development of cyclic peptide ligands for human erythropoietin,” J.Chrom. A 2017, In Press, Corrected Proof. doi: /10.1016/j.chroma.2017.04.019.

2016

S. Menegatti, B. G. Bobay, K.L. Ward, T. Islam, W.S. Kish, A.D. Naik, R.G. Carbonell, “Design of protease-versistant peptide ligands for the purification of antibodies from human plasma,” J. Chrom. A 2016, doi: /10.1016/j.chroma.2016.03.087.

Menegatti, Stefano, Michael Zakrewsky, Sunny Kumar, Joshua Sanchez De Oliveira, John A. Muraski, and Samir Mitragotri. “De novo design of skin‐penetrating peptides for enhanced transdermal delivery of peptide drugs.” Advanced healthcare materials 5, no. 5 (2016): 602-609.

S. Menegatti, M. Zakrewsky, S. Kumar, J. Sanchez de Oliveira, J. A. Muraski, and S. Mitragotri, “De novo Design of Skin-penetrating Peptides for Enhanced Transdermal Delivery of Peptide Drugs,” Adv. Health. Mater. 2016, doi: 10.1002/adhm.201500634.

Camacho, Kathryn M., Stefano Menegatti, and Samir Mitragotri. “Low-molecular-weight polymer–drug conjugates for synergistic anticancer activity of camptothecin and doxorubicin combinations.” Nanomedicine 11, no. 9 (2016): 1139-1151.

C.M. Camacho, S. Menegatti, D.R. Vogus, A. Pusuluri, Z. Fuchs, M. Jarvis, M. Zakrewski, M.A. Evans, R. Chen, S. Mitragotri, “DAFODIL: A novel liposome-encapsulated synergistic combination of doxorubicin and 5FU for low dose chemotherapy,” J. Control. Release 2016, 229:154-162. doi: 10.1016/j.jconrel.2016.03.027.

F. Shen, O.J. Rojas, J. Genzer, P.V. Gurgel, R.G. Carbonell, “Affinity interactions of human immunoglobulin G with short peptides: role of ligand spacer on binding, kinetics, and mass transfer,” Analytical and bioanalytical chemistry (2015): 1-13.

2015

S. Menegatti, N. Ruocco, S. Kumar, M. Zakrewsky, J. Sanchez de Oliveira, M.E. Helgeson, L.G. Leal, S. Mitragotri, “Synthesis and Characterization of a Self-Fluorescent Hyaluronic Acid-Based Gel for Subcutaneous Applications,” Advanced Healthcare Materials 2015, 4(15): 2297-2305.

K.M. Camacho, S. Kumar, S. Menegatti, D.R. Vogus, A.C. Anselmo, S. Mitragotri, “Synergistic antitumor activity of camptothecin-doxorubicin combinations and their conjugates with hyaluronic acid”, J. Control. Release 2015; 210:198-207. doi: 10.1016/j.jconrel.2015.04.031.

A.C. Anselmo, M. Zhang, S. Kumar, D.R. Vogus, S. Menegatti, M.E. Helgesson, S. Mitragotri, “Elasticity of nanoparticles influences their blood circulation, phagocytosis, endocytosis, and targeting”, ACS Nano 2015; 9(3):3169-77. doi: 10.1021/acsnano.5b00147.

S. Kumar, M. Zakrewsky, M. Chen, S. Menegatti, J. A. Muraski, and S. Mitragotri, “Peptides as skin penetration enhancers: mechanisms of action, J. Control. Release 2014, doi: 10.1016/j.jconrel.2014.12.006.

H. Liu, P.V. Gurgel, R.G. Carbonell, “Preparation and characterization of anion exchange adsorptive nonwoven membranes with high protein binding capacity.” Journal of Membrane Science 493 (2015): 349-359.

2014

Aaron C. Anselmo, Christa L. Modery-Pawlowski, Stefano Menegatti, Sunny Kumar, Lewis L. Tian, Ming Chen, Anirban Sen Gupta, and Samir Mitragotri, “Platelet-like Nanoparticles (PLNs): engineering shape, flexibility and surface chemistry to nanocarriers to target vascular injuries,” ACS Nano 2014, 8(11), 11243-53.

N. Islam, F. Shen, P.V. Gurgel, O.J. Rojas, R.G. Carbonell,  “Dynamic and equilibrium performance of sensors based on short peptide ligands for affinity adsorption of human IgG using surface plasmon resonance,” Biosensors and Bioelectronics 58 (2014): 380-387.

J.M. Billakanti, C.J. Fee, A.D. Naik, R.G. Carbonell, “Application of peptide chromatography for the isolation of antibodies from bovine skim milk, acid whey and colostrum.” Food and Bioproducts Processing 92.2 (2014): 199-207.

N. Islam, P.V. Gurgel, O.J. Rojas, R.G. Carbonell, “Effects of composition of oligo (ethylene glycol)-based mixed monolayers on peptide grafting and human immunoglobulin detection.” The Journal of Physical Chemistry C 118.10 (2014): 5361-5373.

2013

Stefano Menegatti, Kevin L. Ward, Amith D. Naik, William S. Kish, Robert K. Blackburn, and Ruben G. Carbonell, Reversible cyclic peptide libraries for the discovery of affinity ligands, Anal. Chem. 2013, 85(19), 9229-9237.

Stefano Menegatti, Amith D. Naik, and Ruben G. Carbonell, The hidden potential of small synthetic molecules and peptides as affinity ligands for bioseparation, Pharm. Bioprocessing 2013, 1(5), 467-485.

Y. Zhang, R.G. Carbonell, O.J. Rojas, “Bioactive cellulose nanofibrils for specific human IgG binding.” Biomacromolecules 14.12 (2013): 4161-4168.

Y. Zhang, N. Islam, R.G. Carbonell, O.J. Rojas, “Specificity and regenerability of short peptide ligands supported on polymer layers for immunoglobulin G binding and detection.” ACS applied materials & interfaces 5.16 (2013): 8030-8037.

R.F. Susanti, Y.S. Han, J. Kim, Y.H. Lee, R.G. Carbonell, “A new strategy for ultralow biofouling membranes: Uniform and ultrathin hydrophilic coatings using liquid carbon dioxide.” Journal of Membrane Science 440 (2013): 88-97.

Z. Liu, P.V. Gurgel, R.G. Carbonell, “Affinity chromatographic purification of human immunoglobulin a from chinese hamster ovary cell culture supernatant.” Biotechnology progress 29.1 (2013): 91-98.

Z. Liu, P.V. Gurgel, R.G. Carbonell, “Affinity chromatographic purification of human immunoglobulin M from human B lymphocyte cell culture supernatant.” Biochemical Engineering Journal 70 (2013): 63-70.

Y. Zhang, N. Islam, R.G. Carbonell, O.J. Rojas, “Specific binding of immunoglobulin G with bioactive short peptides supported on antifouling copolymer layers for detection in quartz crystal microgravimetry and surface plasmon resonance.” Analytical chemistry 85.2 (2012): 1106-1113.

H. Liu, Y. Zheng, P.V. Gurgel, R.G. Carbonell, “Affinity membrane development from PBT nonwoven by photo-induced graft polymerization, hydrophilization and ligand attachment.” Journal of Membrane Science 428 (2013): 562-575.

2012

Stefano Menegatti, Amith D. Naik, Patrick V. Gurgel, and Ruben G. Carbonell, Alkaline-stable peptide ligand affinity adsorbents for the purification of biomolecules, J. Chromatogr. A 2012, 1245:55-64.

Stefano Menegatti, Mahmud Hussain, Amith D. Naik, Balaji M. Rao, and Ruben G. Carbonell, mRNA display selection and solid-phase synthesis of Fc-binding cyclic peptide affinity ligands, Biotechnol. Bioeng. 2012, 110(3), 857-870.

Stefano Menegatti, Amith D. Naik, Patrick V. Gurgel, and Ruben G. Carbonell, Purification of polyclonal antibodies from Cohn Fraction II+III, skim milk and whey by affinity chromatography using hexamer peptide ligand, J. Sep. Sci. 2012, 35(22): 3139-3148.

William S. Kish, Amith D. Naik, Stefano Menegatti, and Ruben G. Carbonell, Peptide-based affinity adsorbents with high binding capacity for the purification of monoclonal antibodies, Ind. Eng. Chem. Res. 2012, 52(26), 8800-8811

Amith D. Naik, Stefano Menegatti, Patrick V. Gurgel, and Ruben G. Carbonell, Process for Purification of Monoclonal Antibody Expressed in Transgenic Lemna Plant Extract Using Dextran- Coated Charcoal and Hexamer Peptide Affinity Resin, J. Chromatogr. A 2012, 1260:61-66.

2011

Amith D. Naik, Stefano Menegatti, Patrick V. Gurgel, and Ruben G. Carbonell, Performance of hexamer peptide ligands for affinity purification of Immunoglobulin G from commercial cell culture media, J. Chromatogr. A 2011, 1218(13): 1691-1700.

Z. Liu, P.V. Gurgel, R.G. Carbonell, “Effects of peptide density and elution pH on affinity chromatographic purification of human immunoglobulins A and M”, J. Chromatogram. A 2011; 1218(46): 8344-52. doi: 10.1016/j.chroma.2011.09.038.

N. Cain, G. Roberts, D. Kiserow, R.G. Carbonell, “Modeling the thermodynamic and transport properties of decahydronaphthalene/propane mixtures: Phase equilibria, density, and viscosity.” Fluid Phase Equilibria 305.1 (2011): 25-33.

Y. Zheng, P.V. Gurgel, R.G. Carbonell, “Effects of UV exposure and initiator concentration on the spatial variation of poly (glycidyl methacrylate) grafts on nonwoven fabrics.” Industrial & Engineering Chemistry Research 50.10 (2011): 6115-6123.